hrp0094p2-290 | Growth and syndromes (to include Turner syndrome) | ESPE2021

Linear growth response to growth hormone therapy in underweight versus normal-weight children with idiopathic short stature (ISS)

Elawwa Ahmed , Soliman Ashraf , ElSiddig Sohair , Farag Marwa ,

Introduction: Growth hormone (GH) increases lean body mass and reduces fat mass. However, the long-term changes in weight status during growth hormone treatment, according to age and weight status at the onset of treatment, have not previously been reported in large data sets.Aim: To identify the growth response to GH therapy in underweight versus normal weight short children.Patients and Methods: ...

hrp0094p2-12 | Adrenals and HPA Axis | ESPE2021

Defective Cortisol Secretion in Response to Spontaneous Hypoglycemia but Normal Cortisol Response to ACTH stimulation in neonates with Hyperinsulinemic Hypoglycemia (HH).

Ahmed Shayma , Soliman Ashraf , Alyafie Fawzia , Alaaraj Nada , Hamed Noor , Farag Marwa ,

Introduction: Hyperinsulinaemic Hypoglycaemia (HH) is the most common cause of recurrent and persistent hypoglycemia in the neonatal period. Cortisol and GH play an important role as counterregulatory hormones during hypoglycemia. Both antagonize the peripheral effects of insulin and directly influence glucose metabolism.Patients and Methods: We studied cortisol and GH secretion in newborn infants with HH during spontaneous hypoglycemia....